Research Articles · Research Paper P2

The Optimal Electrode Distance in Recording Compound Nerve Action Potentials to Study Traffic Nerve Functional Injury Mechanism

Shengxiong Liu, Shanshan Pu, Junhong Xiang, Daiqin Tao

Forensic Science Seminar · 2021 · Volume 11 · Issue 1 · pp. 9–15

Author note: Shengxiong Liu, Shanshan Pu and Junhong Xiang contributed equally and should be regarded as co-first authors.

Abstract

Abstract

The compound nerve action potential and its conductivity characteristics can be used to study the traffic brain functional injury mechanism. The recording of compound nerve action potentials is greatly affected by the distance between the electrode tips. In order to study the optimum parameters for these recordings in the bullfrog sciatic nerve trunk, compound nerve action potential was measured at different electrode spacing. The threshold and super stimulation intensity of compound nerve action potential were first decreased slowly and then gradually increased as the distance between the tips of the two stimulation electrodes was increased. When the distance between exciting point and recording point was gradually increased, the amplitude and area under the curve were decreased, but the action potential duration was increased. The amplitude, action potential duration and area under the curve had the tendency to improve with the distance between two recording electrode tips increasing from 5 mm to 20 mm. When that spacing was larger than 20 mm, the amplitude was relatively stable. The distance of two stimulating electrodes is 5mm, the distance between stimulating and measuring electrodes is 10mm and the distance of two measuring electrodes is 20mm, which is the most suitable distance for compound nerve action potentials collecting on the bullfrog sciatic nerve trunk.

Keywords: Compound nerve action potential; Traffic nerve functional injury; Amplitude; Area under the curve; Action potential duration

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